Some hypotheses for the design and construction of medicine warehouses for hot-arid and hot-humid climates have been defined and presented in a downloadable booklet. The booklet deals with specific design principles and investigates through energy simulations the thermal performance of some basic building configurations. The considered solutions are aimed to be cheap, easily buildable and suitable to passive cooling even in presence of the high infiltration rates typically deriving from the adoption of low-tech, self-construction methods. The main bioclimatic strategies here exploited are based on thermal mass in water drums, night ventilation and radiative night cooling from the roof, coupled, when viable, with evaporative cooling.